Don't stop tests too early or run them too long. Calculate required duration and sample size before starting.
Sample size calculation: Use a sample size calculator (many free online). Input: baseline conversion rate (current performance), minimum detectable effect (smallest improvement you care about), statistical power (typically 80%), significance level (typically 95%). Output: required sample size per variant. Example: baseline 4% conversion, want to detect 10% lift (4% → 4.4%), need ~15,000 visitors per variant (30,000 total). If your page gets 2,000 visitors/month, the test will take 15 months. Not feasible. Either test a higher-traffic page or test a larger effect size.
Test duration calculation: Minimum 2 weeks to account for day-of-week variation (B2B traffic patterns weekly). Minimum through 1 full business cycle (if you're B2B with monthly sales cycles, run test through full month). Maximum 8 weeks (after 8 weeks, external factors change too much to attribute results cleanly). If you can't reach sample size within 8 weeks, either accept lower confidence level or don't run the test.
Early stopping rules: Generally, don't stop tests early. "We're up 15% after 3 days!" is often regression to the mean. But you can set pre-defined stopping rules: if variant is worse by >20% after reaching 50% of required sample size, stop for safety (you're harming conversion). If variant is better by >30% after reaching 75% of sample, you can stop early (result is clear). These rules must be set before starting, not decided during the test.
Simultaneous tests: Can you run multiple tests at once? Yes, but be careful of interactions. Testing homepage headline and pricing page CTA simultaneously is fine (different pages, different visitors). Testing headline and CTA on the same page simultaneously requires multivariate approach (test all combinations). Testing two headline variants on the same page (A/B/C test) splits traffic three ways, requires 50% more traffic to reach significance.